Name: Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Prep time: 15 min
Cook time: 35 min
Total time: 50 min
Cuisine: Italian
Ingredients: 12 uncooked lasagna noodles; 1 teaspoon salt; 3 cups cooked shredded chicken; 2 cups shredded mozzarella cheese; 2 tablespoons chopped fresh parsley (for garnish); ⅓ cup butter; 3 cloves garlic; 1 tablespoon all-purpose flour; 1½ cups milk (2% or whole); 1 cup heavy whipping cream; ¾ cup parmesan cheese; ½ teaspoon salt; ¼ teaspoon ground black pepper; ⅛ teaspoon ground nutmeg (optional)

There's nothing quite like the rich, velvety texture of a classic Italian dish to lift your dinner mood. This Creamy Chicken Alfredo Lasagna Roll Ups Recipe blends tender shredded chicken with luscious alfredo sauce, all wrapped up in pillowy noodles—and it’s a total crowd-pleaser that’s easier to make than traditional lasagna!

A close-up of a single rolled piece of lasagna held on a wooden spatula, showing about three wavy pasta layers filled with thick white creamy sauce mixed with melted cheese, some cheese strings stretching down, and a golden-baked top layer with light browning and small bits of green herbs sprinkled on it, all set against a white marbled texture background photo taken with an iphone --ar 2:3 --v 7

Jump to:

Why You'll Love This Recipe
Ingredients & Why They Work
Make It Your Way
Step-by-Step: How I Make Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Top Tip
How to Serve Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Make Ahead and Storage
Frequently Asked Questions:
Final Thoughts
Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Why You'll Love This Recipe

I remember the first time I made these roll ups; the creamy sauce and cheesy chicken filling won me over instantly. This recipe turns a typically time-consuming meal into joyous weeknight comfort food, and it’s incredibly forgiving for newbie cooks.

Simple yet decadent: All the flavors of chicken alfredo in a handheld, bake-friendly package.
Great for meal prep: Make several ahead and reheat easily without losing creaminess.
Customizable: You can swap chicken for veggies or add herbs to make it your own.
Family-friendly: Even picky eaters tend to love the cheesy, creamy texture.

The dish shows a white rectangular baking dish filled with a neatly arranged layer of pasta squares, likely lasagna sheets, lightly golden on top with melted cheese browned in some spots. The top layer is creamy and slightly bubbly with small green herb sprinkles scattered evenly. The layers beneath show more pasta squares slightly visible through the edges, covered in a rich white sauce. The baking dish rests on a white marbled surface, adding a clean, bright background to the warm, cheesy comfort food photo taken with an iphone --ar 2:3 --v 7

Ingredients & Why They Work

This dish combines a handful of simple ingredients, each bringing a specific role—like the creamy sauce that’s the star, the chicken for protein, and the noodles to bring it all together with perfect chew.

Flat lay of uncooked rectangular lasagna noodles neatly stacked, a small white bowl of light golden melted butter, three whole uncracked garlic cloves, a small white bowl of pale beige all-purpose flour, a small white bowl filled with creamy white milk, a small white bowl filled with rich heavy whipping cream, a small white bowl of finely grated pale yellow parmesan cheese, a small white bowl with coarse salt crystals, a small white bowl with ground black pepper, a small white bowl with a pinch of light brown ground nutmeg, a simple mound of cooked shredded white chicken breast, a small white bowl overflowing with shredded white mozzarella cheese, and a small handful of fresh bright green chopped parsley, all ingredients arranged symmetrically and balanced on a clean white marble surface, soft natural light, photo taken with an iPhone, professional food photography style, fresh ingredients, white ceramic bowls, no bottles, no duplicates, no utensils, no packaging --ar 2:3 --v 7 --p m7354615311229779997

Uncooked lasagna noodles: Using uncooked noodles cooked al dente prevents mushiness; soaking them in room temp water stops sticking.
Butter: Melts into a base for that buttery, rich Alfredo sauce flavor.
Garlic: Fresh cloves add fragrant warmth; I always use fresh rather than powdered here.
All-purpose flour: Thickens the sauce into that creamy comfort consistency you expect.
Milk (2% or whole): Keeps the sauce light but still creamy—whole milk adds extra richness, which I love for this one.
Heavy whipping cream: Cranks the "creaminess" level up for that silky smooth sauce; skip if you want it lighter but expect less indulgence.
Parmesan cheese: Adds a sharp, nutty flavor and helps thicken your sauce while contributing its famous melt.
Salt & pepper: Essential for balancing and enhancing the flavors—don’t skimp here.
Ground nutmeg (optional): A pinch of nutmeg brings out the garlic and cheese flavors subtly and warms the sauce.
Cooked shredded chicken: Using leftover roasted chicken works perfectly, or you can poach breasts quickly for fresh, tender meat.
Mozzarella cheese: Melts beautifully inside for gooey pockets in every bite.
Fresh parsley: Adds a pop of color and fresh herbal brightness as a finishing garnish.

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Note: You'll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Make It Your Way

I love playing around with this recipe depending on the season and who I'm feeding. Sometimes I sneak in spinach or artichoke hearts for some extra veggie love, and my kids adore it when I swap out the mozzarella for provolone.

Variation: Once, I swapped chicken with sautéed mushrooms and spinach to make a vegetarian version, and it was just as satisfying—creamy without the meat.
Dairy-free switch: Use coconut cream and vegan cheese for a dairy-free take, though the texture and flavor will shift a bit, it still pleases nicely.
Herbs & spices: Toss in some basil or Italian seasoning for extra herbal depth, especially if you’re pairing it with a tomato-based side.

Step-by-Step: How I Make Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Step 1: Cook the noodles perfectly

Bring a large pot of salted water to a boil and cook your lasagna noodles until al dente. This typically means just a minute or two less than package directions say. Drain and immediately place them in a pot with room temperature water—trust me on this—it prevents sticking and makes rolling easier. I always do this step first and set the noodles aside while I prepare the sauce.

Step 2: Whip up the creamy Alfredo sauce

In a skillet, melt your butter over medium heat and add minced garlic until it smells heavenly—about one minute. Stir in the flour and cook a minute more; this step avoids a raw flour taste. Slowly whisk in the milk and heavy cream, letting it gently simmer and thicken for a couple minutes. Then add parmesan, salt, pepper, and that pinch of nutmeg. Keep whisking until everything melds into a luscious sauce. If your sauce gets too thick, a splash more milk loosens it up—though I’ve rarely had that happen.

Step 3: Mix chicken with sauce and cheese

Save about a cup of the Alfredo sauce for the base of your baking dish. In a bowl, combine the remaining sauce with shredded chicken and a cup of mozzarella. Salt and pepper it well here to ensure the filling sings when baked. This mix is the creamy filling you’ll spread on the noodles before rolling.

Step 4: Roll, assemble, and bake

Lay each noodle flat, pat dry carefully, then spread an even layer of the chicken mixture and roll it up tightly. Place each roll seam-side down in your greased baking dish with that reserved sauce spread on the bottom. Top everything with remaining mozzarella and bake at 375°F (190°C) until golden and bubbly, about 25-30 minutes.

Top Tip

Over the years, I've learned a few tricks that take this dish from good to unforgettable. These tips make the cooking process smoother and help keep your roll ups creamy and delicious every time.

Prevent sticky noodles: Soaking in room temp water after cooking is a game-changer—otherwise, they start sticking before you even fill them.
Control sauce thickness: Add liquid slowly when whisking the sauce—it's easier to thin than to fix if it’s too thick.
Roll gently but firmly: Press a little when rolling, so the filling stays nicely inside and the rolls keep shape in the pan.
Don’t overbake: Bake just until bubbly and golden; overbaking dries the sauce and noodles.

How to Serve Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Chicken Alfredo Lasagna Roll Ups - Serving Suggestion

Garnishes

I always sprinkle fresh chopped parsley on top—it brightens the dish visually and adds a fresh herbaceous note that balances the richness. A little extra parmesan on the side never hurt either!

Side Dishes

To keep things balanced, I usually pair this with a crisp green salad dressed lightly with lemon vinaigrette or some roasted garlic broccoli. A simple garlic bread doesn’t hurt for those carb lovers in your crowd.

Creative Ways to Present

For special dinners, I've arranged the roll ups in a circle on a large platter, adding fresh basil leaves around and drizzling a touch of balsamic glaze. It turns the comforting meal into a beautiful centerpiece that feels festive and elegant.

Make Ahead and Storage

Storing Leftovers

Leftovers store beautifully in an airtight container in the fridge for up to 3 days. The creamy sauce holds moisture well, so reheated portions are still rich and satisfying.

Freezing

I sometimes make a double batch and freeze before baking. Wrap each roll up tightly in foil or plastic wrap, place in a freezer bag, and they'll keep for up to 2 months. When you're ready, thaw overnight in the fridge before baking.

Reheating

To reheat, cover the baking dish with foil to avoid drying out, and warm in a 350°F oven until heated through—about 15-20 minutes. Microwave is quick in a pinch but can make the noodles a bit gummy if overheated.

Frequently Asked Questions:

Can I use store-bought Alfredo sauce instead?

Yes! Using a good quality store-bought Alfredo sauce can save you time. However, homemade sauce gives you control over thickness and flavor and tends to be fresher and less salty.

What type of chicken works best for this recipe?

Cooked shredded chicken works best—whether from leftover rotisserie, poached breasts, or even grilled chicken. The goal is tender, shredded pieces that mix well with the sauce.

Can this be made gluten-free?

Absolutely! Use gluten-free lasagna noodles and substitute all-purpose flour with a gluten-free alternative like tapioca or rice flour in your sauce. Make sure all other ingredients are gluten-free certified.

How do I prevent the noodles from sticking during assembly?

After cooking, placing noodles in room temperature water keeps them from sticking as you assemble. Also, working gently to dry each noodle before adding filling helps. Rubbing a little bit of olive oil on them can be helpful too.

Final Thoughts

This Creamy Chicken Alfredo Lasagna Roll Ups Recipe is one of those dishes that feels fancy but is really relaxed to make—and that’s why I come back to it over and over. Whether it’s cozy family dinners or feeding a crowd, these roll ups hit every note: creamy, cheesy, comforting, and satisfying. Give it a try—you might find it becoming your next weeknight favorite!